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DKK3 in HNSCC

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Establishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC).

Katase N, Nishimatsu S, Yamauchi A, Okano S, Fujita S.

Cancer Cell Int. 2022 Nov 15;22(1):352.

DKK3_CKAP4-2.jpg

DKK3/CKAP4 axis is associated with advanced stage and poorer prognosis in oral cancer.

Katase N, Kudo K, Ogawa K, Sakamto Y, Nishimatsu S, Yamauchi A, Fujita S.

Oral Dis. 2022 [in press]

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DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways.

Katase N, Nishimatsu SI, Yamauchi A, Yamamura M, Fujita S.

Int J Oncol. 2018 Dec 14. doi: 10.3892/ijo.2018.4667.

Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells.

Katase N, Lefeuvre M, Tsujigiwa H, Fujii M, Ito S, Tamamura R, Buery RR, Gunduz M, Nagatsuka H.

Oncol Rep. 29(4):1349-55. 2013

Knockdown of Dkk-3 decreases cancer cell migration and invasion independently of the Wnt pathways in oral squamous cell carcinoma‑derived cells.

Katase N, Lefeuvre M, Tsujigiwa H, Fujii M, Ito S, Tamamura R, Buery RR, Gunduz M, Nagatsuka H.

Oncol Rep. 29(4):1349-55. 2013

Absence of Dickkopf (Dkk)-3 protein expression is correlated with longer disease-free survival and lower incidence of metastasis in head and neck squamous cell carcinoma.

Katase N, Lefeuvre M, Gunduz M, Gunduz E, Beder LB, Grenman R, Fujii M, Tamamura R, Tsujigiwa H, Nagatsuka H.

Oncol Lett. 3(2):273-280. 2012

Dickkopf (Dkk)-3 and β-catenin expressions increased in the transition from normal oral mucosal to oral squamous cell carcinoma.

Fujii M, Katase N, Lefeuvre M, Gunduz M, Buery RR, Tamamura R,

Tsujigiwa H, Nagatsuka H.

J Mol Histol.  42(6):499-504. 2011

Deletion at Dickkopf (dkk)-3 locus (11p15.2) is related with lower lymph node metastasis and better prognosis in head and neck squamous cell carcinomas.

Katase N, Gunduz M, Beder L, Gunduz E, Lefeuvre M, Hatipoglu OF, Borkosky SS, Tamamura R, Tominaga S, Yamanaka N, Shimizu K, Nagai N, Nagatsuka H.

Once Res. 17(6):273-82. 2008

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